Watertown, MA

At Neumora, we are pushing the boundaries of science and technology to revolutionize the way patients with brain disease are treated. We are seeking extraordinary individuals to join our team as we grow and advance our pipeline.

Brain disorders are the leading cause of disability and death in the world, and current treatments are inadequate. There are multiple reasons for this: treatments are not targeted; patients experience delayed and partial treatment responses; and brain disorders are treated based on the diagnoses of heterogeneous disease populations. We are sitting at a critical intersection. The convergence of recent advancements in human genomics and real-world clinical data make possible the emergence of a game-changing innovator in brain science. Enter Neumora, with the mission to transform the treatment of brain disorders through precision medicine. Co-located in Boston and the San Francisco Bay Area, Neumora is building a world-class team backed by leading investors, including ARCH Venture Partners and long-term, mission/vision-oriented investors. Neumora recently raised more than $500M in its Series A and entered into a strategic R&D collaboration with Amgen. Neumora is currently at ~100 employees and well-positioned for further growth.

We are seeking an accomplished Physician Scientist with experience in early clinical development and translational science to join our clinical team, reporting to the Chief Medical Officer (CMO). The successful candidate will contribute to the strategic planning and execution of translational and early clinical studies to support assessment of safety and pharmacokinetics, demonstration of target engagement, proof-of-mechanism and where possible early signal of efficacy in support of a diverse portfolio of projects in psychiatric and neurodegenerative diseases. The individual will lead and work on multiple projects with an integrated team of neuroscientists, clinicians and data scientists. To thrive in the role the individual will have strong background in early clinical development and translational neuroscience across neuropsychiatric and neurodegenerative disorders and will be well-versed in the multifaceted nature of neuroscience drug discovery.

Responsibilities:

• Lead the strategic design and execution of early clinical development programs leveraging Neumora's precision neuroscience approach.
• Ensure early clinical programs support patient safety and to provide oversight of patient safety in clinical trials.
• Provide clinical development and medical leadership/oversight of early clinical programs to ensure timely delivery of program milestones.
• Work with key stake-holders to evaluate and integrate appropriate pharmacodynamic and biomarker endpoints (e.g., fluid, neurophysiological) and data-driven patient enrichment strategies into study designs.
• Effectively communicate clinical development plans to project teams and senior management to facilitate decision making.
• Establish and manage collaborations and studies with external partners.
• Participate in regulatory document preparation including report writing and review, and in interactions with regulatory authorities.
• Present data at scientific conferences and publish in peer-reviewed journals as applicable.
• Support business development activities.

The ideal individual is self-motivated, detail-oriented and exhibits strength in the ability to prioritize and execute multiple projects simultaneously. The individual must work effectively within an organization and demonstrate reliability, responsivity and a relentless focus to Neumora's mission. We are particularly interested in individuals who possess exceptional oral and written communication skills, who exhibit drive, candor and a commitment to learning.

Requirements:

• US Board Certified / Board eligible / ex-US equivalent
• Track record of successful early clinical development and translational leadership, incorporation of innovative clinical trial design and strategy experience in a biotech or pharmaceutical therapeutics organization.
• Experience interacting with regulatory agencies, CROs, and central laboratory vendors.
• Demonstrated ability to evaluate, interpret and present complex scientific data
• Strong pro-active problem-solver who adapts, thrives and leads and delivers results in a dynamic, fast-paced work environment.
• Adaptable and able to prioritize and allocate resources with agility to meet goals.
• The ability to build and maintain excellent interpersonal relationships, both within and outside the company, at all levels.

#LI-Hybrid

To the fullest extent permitted by applicable law, Employment is conditioned upon individuals being up-to-date with COVID-19 vaccines (in accordance with current CDC guidelines), including submission of documented proof thereof, as of the start date. Neumora will comply with applicable law regarding the reasonable accommodation of individuals who are not up-to-date with COVID-19 vaccines because of a disability and/or sincerely held religious belief.

Neumora is a clinical-stage biopharmaceutical company pioneering the development of novel precision medicines for brain diseases. By leveraging an integrated understanding of the multidimensional systems that drive brain diseases in specific patient groups, we aim to provide impactful, targeted therapeutic options for neuropsychiatric and neurodegenerative conditions with significant unmet need.

Neumora is an equal opportunity employer and will not discriminate against any employee or applicant on the basis of age, color, disability, gender, national origin, race, religion, sexual orientation, veteran status, or any classification protected by federal, state, or local law.